{"id":1575,"date":"2024-06-06T11:05:51","date_gmt":"2024-06-06T10:05:51","guid":{"rendered":"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/?p=1575"},"modified":"2024-06-06T11:05:51","modified_gmt":"2024-06-06T10:05:51","slug":"new-results-from-the-study-research-on-bdmards-and-rheumatoid-arthritis","status":"publish","type":"post","link":"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/2024\/06\/06\/new-results-from-the-study-research-on-bdmards-and-rheumatoid-arthritis\/","title":{"rendered":"New results from the study: Research on bDMARDs and Rheumatoid Arthritis"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; fullwidth=&#8221;on&#8221; next_background_color=&#8221;#000000&#8243; global_module=&#8221;322&#8243;][et_pb_fullwidth_menu global_parent=&#8221;322&#8243; _builder_version=&#8221;3.0.106&#8243; menu_id=&#8221;7&#8243; submenu_direction=&#8221;downwards&#8221; fullwidth_menu=&#8221;off&#8221; background_layout=&#8221;dark&#8221; module_class=&#8221;main-navigation&#8221; \/][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; fullwidth=&#8221;off&#8221; specialty=&#8221;on&#8221; prev_background_color=&#8221;#000000&#8243; next_background_color=&#8221;#1d1d1d&#8221;][et_pb_column type=&#8221;2_3&#8243; specialty_columns=&#8221;2&#8243;][et_pb_row_inner locked=&#8221;off&#8221;][et_pb_column_inner type=&#8221;4_4&#8243; saved_specialty_column_type=&#8221;2_3&#8243;][et_pb_post_title _builder_version=&#8221;3.17.6&#8243; featured_placement=&#8221;above&#8221; locked=&#8221;on&#8221; parent_locked=&#8221;off&#8221; date_format=&#8221;j M Y&#8221; \/][et_pb_text _builder_version=&#8221;3.17.6&#8243; background_layout=&#8221;light&#8221; parent_locked=&#8221;off&#8221;]<\/p>\n<p>We are happy to share our latest research findings: &#8216;Evaluation of serious infections, including Mycobacterium tuberculosis, during<img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-1572\" src=\"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-content\/uploads\/sites\/440\/2024\/05\/Kim-Lauper-225x300.jpg\" alt=\"Dr Kim Lauper\" width=\"225\" height=\"300\" srcset=\"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-content\/uploads\/sites\/440\/2024\/05\/Kim-Lauper-225x300.jpg 225w, https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-content\/uploads\/sites\/440\/2024\/05\/Kim-Lauper-150x200.jpg 150w, https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-content\/uploads\/sites\/440\/2024\/05\/Kim-Lauper-250x333.jpg 250w, https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-content\/uploads\/sites\/440\/2024\/05\/Kim-Lauper-350x466.jpg 350w, https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-content\/uploads\/sites\/440\/2024\/05\/Kim-Lauper.jpg 460w\" sizes=\"(max-width: 225px) 100vw, 225px\" \/> treatment with biologic disease-modifying antirheumatic drugs: does line of therapy matter?&#8217;<\/p>\n<p>This analysis, performed by Dr Kim Lauper, looks into the incidence of serious infections and active tuberculosis among seven biological DMARDs in rheumatoid arthritis patients using data from 33,897 patients in the BSRBR-RA study.<\/p>\n<h2>Key Take-aways<\/h2>\n<ol>\n<li>The risk of serious infections remains consistent across therapy lines.<\/li>\n<li>Tuberculosis risk is notably higher in the early treatment phases or before 2009.<\/li>\n<li>When comparing the effects of treatments on events, it&#8217;s essential to account for the line of therapy and\/or the year of treatment initiation, especially for conditions such as TB, where management has undergone significant changes over time.<\/li>\n<\/ol>\n<p>Read the full paper in the journal <a href=\"https:\/\/academic.oup.com\/rheumatology\/advance-article\/doi\/10.1093\/rheumatology\/kead515\/7284107\">Rheumatology<\/a>.<\/p>\n<p>[\/et_pb_text][et_pb_post_nav _builder_version=&#8221;3.0.106&#8243; 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--relposth-columns_m: 2\"><a href=\"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/2024\/08\/01\/jak-inhibitors-in-the-bsrbr-ra\/\"class=\"relpost-block-single\" ><div class=\"relpost-custom-block-single\"><div class=\"relpost-block-single-image rpt-lazyload\" aria-label=\"Charts and graphs with a magnifying glass lying on top of them.\" role=\"img\" data-bg=\"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-content\/uploads\/sites\/440\/2024\/01\/close-look-at-data-150x150.jpg\" style=\"background: transparent no-repeat scroll 0% 0%; width: 150px; height: 150px; aspect-ratio: 1\/1;\"><\/div><div class=\"relpost-block-single-text\"  style=\"height: 75px;font-family: Arial;  font-size: 12px;  color: #333333;\"><h2 class=\"relpost_card_title\">JAK Inhibitors in the BSRBR-RA<\/h2><\/div><\/div><\/a><a href=\"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/2024\/05\/23\/read-about-some-of-the-recent-research-from-that-bsrbr-ra-looking-at-biosimilars\/\"class=\"relpost-block-single\" ><div class=\"relpost-custom-block-single\"><div class=\"relpost-block-single-image rpt-lazyload\" aria-label=\"Charts and graphs with a magnifying glass lying on top of them.\" role=\"img\" data-bg=\"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-content\/uploads\/sites\/440\/2024\/01\/close-look-at-data-150x150.jpg\" style=\"background: transparent no-repeat scroll 0% 0%; 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This analysis, performed by Dr Kim Lauper, looks into the incidence of serious infections and active tuberculosis among seven biological DMARDs in rheumatoid arthritis patients using data [&hellip;]<\/p>\n","protected":false},"author":7109,"featured_media":1488,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_exactmetrics_skip_tracking":false,"footnotes":""},"categories":[9,10],"tags":[],"class_list":["post-1575","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","category-study-results"],"_links":{"self":[{"href":"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-json\/wp\/v2\/posts\/1575","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-json\/wp\/v2\/users\/7109"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-json\/wp\/v2\/comments?post=1575"}],"version-history":[{"count":4,"href":"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-json\/wp\/v2\/posts\/1575\/revisions"}],"predecessor-version":[{"id":1601,"href":"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-json\/wp\/v2\/posts\/1575\/revisions\/1601"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-json\/wp\/v2\/media\/1488"}],"wp:attachment":[{"href":"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-json\/wp\/v2\/media?parent=1575"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-json\/wp\/v2\/categories?post=1575"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.manchester.ac.uk\/bsrbr-blog\/wp-json\/wp\/v2\/tags?post=1575"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}