{"id":2568,"date":"2020-04-27T10:27:10","date_gmt":"2020-04-27T09:27:10","guid":{"rendered":"https:\/\/blogs.manchester.ac.uk\/hcri\/?p=2568"},"modified":"2021-12-10T09:45:29","modified_gmt":"2021-12-10T09:45:29","slug":"a-global-outlook-humanitarian-insight-within-covid-19-clinical-research","status":"publish","type":"post","link":"https:\/\/blogs.manchester.ac.uk\/hcri\/2020\/04\/27\/a-global-outlook-humanitarian-insight-within-covid-19-clinical-research\/","title":{"rendered":"A global outlook: Humanitarian insight within COVID-19 clinical research"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; fullwidth=&#8221;on&#8221; next_background_color=&#8221;#000000&#8243; global_module=&#8221;322&#8243;][et_pb_fullwidth_menu global_parent=&#8221;322&#8243; _builder_version=&#8221;3.0.106&#8243; menu_id=&#8221;7&#8243; submenu_direction=&#8221;downwards&#8221; fullwidth_menu=&#8221;off&#8221; background_layout=&#8221;dark&#8221; module_class=&#8221;main-navigation&#8221; \/][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; fullwidth=&#8221;off&#8221; specialty=&#8221;on&#8221; prev_background_color=&#8221;#000000&#8243; next_background_color=&#8221;#1d1d1d&#8221;][et_pb_column type=&#8221;2_3&#8243; specialty_columns=&#8221;2&#8243;][et_pb_row_inner locked=&#8221;off&#8221;][et_pb_column_inner type=&#8221;4_4&#8243; saved_specialty_column_type=&#8221;2_3&#8243;][et_pb_post_title _builder_version=&#8221;3.0.106&#8243; title=&#8221;on&#8221; meta=&#8221;on&#8221; author=&#8221;on&#8221; date=&#8221;on&#8221; categories=&#8221;on&#8221; comments=&#8221;on&#8221; featured_image=&#8221;on&#8221; featured_placement=&#8221;above&#8221; text_color=&#8221;dark&#8221; text_background=&#8221;off&#8221; locked=&#8221;on&#8221; parent_locked=&#8221;off&#8221; \/][et_pb_text _builder_version=&#8221;3.17.6&#8243; background_layout=&#8221;light&#8221; parent_locked=&#8221;off&#8221;]<\/p>\n<p><em>As with many academics <a href=\"https:\/\/www.research.manchester.ac.uk\/portal\/paul.m.dark\">Professor Paul Dark<\/a> wears a number of different hats including clinician and humanitarian. It\u2019s through these combined disciplines that he is often looking at the wider impact his research can have.\u00a0<\/em><\/p>\n<p><strong>Greater Manchester\u2019s response to COVID-19<\/strong><\/p>\n<p><a href=\"https:\/\/blogs.manchester.ac.uk\/hcri\/wp-content\/uploads\/sites\/325\/2021\/12\/Paul-Dark-2017-e1587983163213-300x258.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-2569 alignleft\" src=\"https:\/\/blogs.manchester.ac.uk\/hcri\/wp-content\/uploads\/sites\/325\/2021\/12\/Paul-Dark-2017-e1587983163213-300x258-300x258.jpg\" alt=\"Professor Paul Dark\" width=\"300\" height=\"258\" srcset=\"https:\/\/blogs.manchester.ac.uk\/hcri\/wp-content\/uploads\/sites\/325\/2021\/12\/Paul-Dark-2017-e1587983163213-300x258.jpg 300w, https:\/\/blogs.manchester.ac.uk\/hcri\/wp-content\/uploads\/sites\/325\/2021\/12\/Paul-Dark-2017-e1587983163213-300x258-150x129.jpg 150w, https:\/\/blogs.manchester.ac.uk\/hcri\/wp-content\/uploads\/sites\/325\/2021\/12\/Paul-Dark-2017-e1587983163213-300x258-250x215.jpg 250w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a>In his role as NIHR National Research Lead for Critical Care and consultant at Salford Royal NHS Foundation Trust, Paul is one of a number of national research\u00a0leads advising the Department of Health and Social Care on <a href=\"https:\/\/www.nihr.ac.uk\/covid-19\/\">Urgent Public Health<\/a> research into vaccines, treatments and diagnostic tests. He is also playing a key role in Greater Manchester <a href=\"https:\/\/www.manchester.ac.uk\/coronavirus-response\/projects\/accelerating-trials\/\">accelerated clinical studies<\/a> into the treatment and care of COVID-19 patients.<\/p>\n<p>This has seen Paul and national colleagues set up a series of observational, treatment and medical evaluation studies in a matter of weeks to help the global response against the virus. An example of this is the newly launched <a href=\"https:\/\/warwick.ac.uk\/fac\/sci\/med\/research\/ctu\/trials\/recovery-rs\/\">RECOVERY-RS Respiratory Support<\/a> study, led by the University of Warwick, which Paul is national co-investigator for.<\/p>\n<p>The study sets out to compare three different treatments that can help a patient with their breathing. The aim is to identify which methods are best at keeping oxygen levels adequate and help prevent the need for mechanical ventilation, where a patient\u2019s breathing is controlled via a machine. This in part may help reduce the high demand for ventilators and the high levels of clinical expertise and oversight needed.<strong>\u00a0<\/strong><\/p>\n<p><strong>The importance of a global approach<\/strong><\/p>\n<p>Paul explains:<\/p>\n<blockquote>\n<p><em>\u201cAs part of my role as Research Professor at the <a href=\"http:\/\/www.hcri.ac.uk\">Humanitarian and Conflict Response Institute<\/a>, I\u2019ve been heavily involved in interdisciplinary collaboration and how we can translate acute care research in low income settings.<\/em><\/p>\n<p>\u00a0<\/p>\n<p><em>\u201cUp until now, the areas most affected by COVID-19 have been high-income countries with relatively stable economies such as China, UK, USA, Italy and France. Quite rightly governments have focused on sourcing additional resource, developing potential vaccines, re-purposing potential drug treatments and expanded equipment such as ventilators to help treat the pandemic. But what will happen in countries where this simply isn\u2019t available?\u201d<\/em><\/p>\n<\/blockquote>\n<p>As the global impact of the COVID-19 pandemic widens, Paul knows that research in the UK could help informs others, specifically developing countries such as those in sub-Saharan Africa. Studies like RECOVERY-RS could have the potential to identify successful treatment methods which do not require large amounts of equipment and funding.<\/p>\n<p><strong>Looking forward<\/strong><\/p>\n<p>Summing up, Paul added:<\/p>\n<blockquote>\n<p><em>\u201cGoing forward, it\u2019s important that we continue to openly share findings, study protocols and insight with colleagues globally, including humanitarian organisations such as\u00a0 <a href=\"https:\/\/www.msf.org.uk\/\">M\u00e9decins Sans Fronti\u00e8res<\/a> and the <a href=\"https:\/\/www.redcross.org.uk\/\">Red Cross<\/a>. The more information we have, the better we can adapt treatment protocols to the setting and resource available.\u201d<\/em><\/p>\n<\/blockquote>\n<p>[\/et_pb_text][et_pb_post_nav _builder_version=&#8221;3.0.106&#8243; in_same_term=&#8221;off&#8221; show_prev=&#8221;on&#8221; show_next=&#8221;on&#8221; prev_text=&#8221;Previous&#8221; next_text=&#8221;Next&#8221; locked=&#8221;on&#8221; parent_locked=&#8221;off&#8221; \/][et_pb_comments _builder_version=&#8221;3.0.106&#8243; show_avatar=&#8221;on&#8221; show_reply=&#8221;on&#8221; show_count=&#8221;on&#8221; background_layout=&#8221;light&#8221; header_font_size_tablet=&#8221;51&#8243; header_line_height_tablet=&#8221;2&#8243; custom_button=&#8221;on&#8221; button_icon_placement=&#8221;right&#8221; button_text_color=&#8221;#ffffff&#8221; button_use_icon=&#8221;off&#8221; locked=&#8221;on&#8221; parent_locked=&#8221;off&#8221; button_text_size__hover_enabled=&#8221;off&#8221; button_text_size__hover=&#8221;null&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; 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It\u2019s through these combined disciplines that he is often looking at the wider impact his research can have.\u00a0Greater Manchester\u2019s response to COVID-19In his role as NIHR National Research Lead for Critical Care and consultant at Salford Royal NHS [&hellip;]<\/p>\n","protected":false},"author":2773,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_exactmetrics_skip_tracking":false,"footnotes":""},"categories":[10,15],"tags":[],"class_list":["post-2568","post","type-post","status-publish","format-standard","hentry","category-covid-19","category-staff-blogs"],"_links":{"self":[{"href":"https:\/\/blogs.manchester.ac.uk\/hcri\/wp-json\/wp\/v2\/posts\/2568","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.manchester.ac.uk\/hcri\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.manchester.ac.uk\/hcri\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.manchester.ac.uk\/hcri\/wp-json\/wp\/v2\/users\/2773"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.manchester.ac.uk\/hcri\/wp-json\/wp\/v2\/comments?post=2568"}],"version-history":[{"count":2,"href":"https:\/\/blogs.manchester.ac.uk\/hcri\/wp-json\/wp\/v2\/posts\/2568\/revisions"}],"predecessor-version":[{"id":2571,"href":"https:\/\/blogs.manchester.ac.uk\/hcri\/wp-json\/wp\/v2\/posts\/2568\/revisions\/2571"}],"wp:attachment":[{"href":"https:\/\/blogs.manchester.ac.uk\/hcri\/wp-json\/wp\/v2\/media?parent=2568"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.manchester.ac.uk\/hcri\/wp-json\/wp\/v2\/categories?post=2568"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.manchester.ac.uk\/hcri\/wp-json\/wp\/v2\/tags?post=2568"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}