What was already known?Juvenile idiopathic arthritis (JIA) is the name given to inflammation in the joints (arthritis) that first occurs in children and young people under the age of 16. It is a painful and disabling condition that can lead to long-term damage.The...
Category: Juvenile idiopathic arthritis
The risk of uveitis in patients with JIA receiving etanercept: the challenges of analysing real-world data.
What was already known? Juvenile idiopathic arthritis (JIA) affects approximately 1 in 1000 children in the UK. Up to one in four of these children will also have serious eye disease associated with their JIA called uveitis. Children with JIA are more likely to...
Obtaining a greater understanding of the causes of Juvenile Idiopathic Arthritis (JIA) and developing new therapies.
What was already known? Juvenile idiopathic arthritis (JIA) is a term used to describe a collection of childhood onset arthritic diseases and as such includes a diverse group of diseases. A classification system has been established by the International League of...
Improved disease activity in patients with systemic JIA treated with tocilizumab or anakinra
What was already known? Biologic therapy is usually given to patients with juvenile idiopathic arthritis (JIA) after they have failed to respond or do not tolerate methotrexate. Patients with systemic JIA do not seem to respond well to tumour necrosis factor...
Early clinically inactive disease and long-term outcomes in juvenile idiopathic arthritis (JIA)
What was already known? Children and young people with JIA and persistent joint pain and swelling are at risk of disability and joint damage in the long-term. The aim for all these patients is a state of 'clinically inactive disease', in which there is no evidence of...
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